Protein-Coated Magnetic Nanoparticles: Creation and Investigation
Electronic Archive of Sumy State University
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
Protein-Coated Magnetic Nanoparticles: Creation and Investigation
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| Creator |
Bychkova, A.V.
Sorokina, O.N. Pronkin, P.G. Tatikolov, A.S. Kovarski, A.L. Rosenfeld, M.A. |
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| Subject |
Stable Coating
Magnetic Nanoparticles Magnetite Adsorption Free Radicals Electron Spin Resonance Spin Labels Ferromagnetic Resonance Fluorescent Probe |
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| Description |
A novel universal approach to cross-linking of protein macromolecules on the surface of magnetite na-noparticles has been developed. The approach is based on protein liability to free radical modification, leading to the formation of intermolecular covalent cross links. Free radicals are locally generated on the surface of nanoparticles. Using a set of physicochemical methods, it has been proven that stable coatings composed of protein macromolecules are formed around individual nanoparticles. The proteins fixed on nanoparticles do not lose their activity as a result of adsorption and free radical modification. Fluorescent probe approach for evaluation of the native functional properties of serum albumin as a part of coating is suggested.
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| Publisher |
Sumy State University
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| Date |
2014-05-29T07:41:07Z
2014-05-29T07:41:07Z 2013 |
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| Type |
Article
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| Identifier |
Protein-Coated Magnetic Nanoparticles: Creation and Investigation [Текст] / A.V. Bychkova, O.N. Sorokina, P.G. Pronkin et al.
// Nanomaterials: Applications & Properties (NAP-2013) : 3-rd International conference, Alushta, the Crimea, Ukraine, September 16-21, 2013 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No2. - 02FNC24
http://essuir.sumdu.edu.ua/handle/123456789/35378 |
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| Language |
en
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