Ultrasonic Nanomedicine in the Therapy of Oncological Diseases
Electronic Archive of Sumy State University
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
Ultrasonic Nanomedicine in the Therapy of Oncological Diseases
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| Creator |
Nikolaev, A.L.
Gopin, A.V. Bozhevolnov, V.E. Mazina, S.E. Treschalina, E.M. Dezhkunov, N.V. |
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| Description |
In this paper the authors develop the concept of using solid-phase nanoscale inclusions in biological structures, as the concentrators of acoustic energy for ultrasound therapy of oncological diseases. Particu-lar attention is paid to possibility of synthesis of these inclusions directly in the tumor tissue. The validity of the hypothesis of solid-phase sonosensitization has been confirmed in vitro on bacterial cultures. Super-additive effect of combined action of ultrasound and solid-phase sonosensitizer on bacterial cultures was shown. Experimental studies on animals showed that the ultrasound exposure of malignant tumors con-taining nanoparticles of gold and some complex compounds (e.g. theraphthal) results in a significant ther-apeutic effect, which is expressed in a considerable inhibition of tumor growth.
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| Publisher |
Sumy State University
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| Date |
2014-05-29T09:51:16Z
2014-05-29T09:51:16Z 2013 |
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| Type |
Article
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| Identifier |
Ultrasonic Nanomedicine in the Therapy of Oncological Diseases [Текст] / A.L. Nikolaev, A.V. Gopin, V.E. Bozhevolnov et al.
// Nanomaterials: Applications & Properties (NAP-2013) : 2-nd International conference, Alushta, the Crimea, September 17-22, 2012 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No4. - 04NABM04
http://essuir.sumdu.edu.ua/handle/123456789/35412 |
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| Language |
en
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