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Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery

Electronic Archive of Sumy State University

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Title Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery
 
Creator Rotar, O.V.
Rotar, V.I.
 
Subject Glutathion
Nanoparticles
Cyclodextrin
Chitosan
 
Description The aim of this study was to investigate an ability of chitosan nanoparticles for tissue delivery of the peptide glutathione. Formulations composed of chitosan or chitosan plus cyclodextrin-beta comlex were prepared. Reduced glutathione was loaded and delivered to mucosal layer of small intestine after ischemia-reperfusion injury more efficiently in chitosan/cyclodextrin-beta nanoparticles. From the data obtained, we believe that chitosan / cyclodextrin nanoparticles can be used for the oral administration of glutathione and other small peptides.
 
Publisher Sumy State University
 
Date 2014-05-29T10:06:52Z
2014-05-29T10:06:52Z
2013
 
Type Article
 
Identifier Rotar, O.V. Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery [Текст] / O.V. Rotar, V.I. Rotar // Nanomaterials: Applications & Properties (NAP-2013) : 2-nd International conference, Alushta, the Crimea, September 17-22, 2012 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No4. - 04NABM07
http://essuir.sumdu.edu.ua/handle/123456789/35422
 
Language en