Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery
Electronic Archive of Sumy State University
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Title |
Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery
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Creator |
Rotar, O.V.
Rotar, V.I. |
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Subject |
Glutathion
Nanoparticles Cyclodextrin Chitosan |
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Description |
The aim of this study was to investigate an ability of chitosan nanoparticles for tissue delivery of the peptide glutathione. Formulations composed of chitosan or chitosan plus cyclodextrin-beta comlex were prepared. Reduced glutathione was loaded and delivered to mucosal layer of small intestine after ischemia-reperfusion injury more efficiently in chitosan/cyclodextrin-beta nanoparticles. From the data obtained, we believe that chitosan / cyclodextrin nanoparticles can be used for the oral administration of glutathione and other small peptides.
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Publisher |
Sumy State University
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Date |
2014-05-29T10:06:52Z
2014-05-29T10:06:52Z 2013 |
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Type |
Article
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Identifier |
Rotar, O.V.
Application of Chitosan / Cyclodextrin Nanoparticles for Tissue Glutathione Delivery [Текст] / O.V. Rotar, V.I. Rotar
// Nanomaterials: Applications & Properties (NAP-2013) : 2-nd International conference, Alushta, the Crimea, September 17-22, 2012 / Edited by: A. Pogrebnjak. - Sumy : Sumy State University, 2013. - V.2, No4. - 04NABM07
http://essuir.sumdu.edu.ua/handle/123456789/35422 |
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Language |
en
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