The Lipid Profile among Patients with Myocardial Infarction Depending on Allelic State of the Genes АСЕ (I/D) and eNOS (T894G)
Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
The Lipid Profile among Patients with Myocardial Infarction Depending on Allelic State of the Genes АСЕ (I/D) and eNOS (T894G)
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| Creator |
Sydorchuk, L.P.
Ursuliak, U.V. |
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| Subject |
polymorphism of genes
acute myocardial infarction lipids |
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| Description |
The changes in lipid profile among patients with acute myocardial infarction (AIM) depending on polymorphism of I/D gene АСЕ, T894G gene eNOS have been researched. The research revealed, that bearing ID-genotype of ACE gene and T-allele gene eNOS is associated with total cholesterol increase (TCI) by 7,88–17,8 %, and DD-genotype – with cholesterol degrease of high density lipoproteins by 38,7 % and 43,2 % accordingly. The complex treatment of AIM patients enhanced the numbers of patients with ‗target‘ TCI level and cholesterol of low density lipoproteins by 44,4 % and 52,4 % accordingly among ID-genotype bearers ACE and T-allele of eNOS gene by 51,1–60,9 %, bearers of II/TG, ID/TT, ID/TG, DD/GG and DD/TG haplotypes – by 29,5–48,6 %. |
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| Date |
2015-05-20T06:02:46Z
2015-05-20T06:02:46Z 2014 |
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| Type |
Other
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| Identifier |
http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/8883
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| Language |
en
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| Format |
application/pdf
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| Publisher |
European Journal of Medicine
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