Protein V, a novel type-II IgG receptor from Streptococcus sp.: sequence, homologies and putative Fc-binding site.
Electronic Archive of Sumy State University
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Title |
Protein V, a novel type-II IgG receptor from Streptococcus sp.: sequence, homologies and putative Fc-binding site.
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Creator |
Смірнов, Олег Ювеналійович
Смирнов, Олег Ювенальевич Smirnov, Oleg Yuvenalyevich Денесюк, Олександр Іванович Денесюк, Александр Иванович Denesiuk, Oleksandr Ivanovych Захаров, Михайло Володимирович Захаров, Михаил Владимирович Zakharov, Mykhailo Volodymyrovych Абрамов, Вячеслав Михайлович Абрамов, Вячеслав Михайлович Abramov, Viacheslav Mykhailovych Зав'ялов, Володимир Петрович Завьялов, Владимир Петрович Zavialov, Volodymyr Petrovych |
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Subject |
recombinant DNA
nucleotide sequence Fc receptor protein structure рекомбинантная ДНК нуклеотидная последовательность Fc рецептор структура белка нуклеотидна послідовність структура білку |
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Description |
We have cloned and sequenced the Fc-receptor-encoding gene, fcrV, from a group G streptococcus. Considerable sim¬ilarity was revealed between the FcRV, FcRA76 and M proteins of group A streptococci in their signal sequences and 3' termini, and between the Fc-binding regions of FcRV and FcRA76. The promoter and terminator regions showed no ho¬mology with those of the fcrA76 and M protein-encoding genes. The A1-A4 domains of FcRV (protein V) exhibit a heptapeptide repeat motif which is characteristic of α-helical coiled-coil proteins. The sequence, Ser-Asn-Arg-Ala-Ala, in the outer position, 'f' of each domain, is highly conserved and may be involved in FcR-IgG interactions.
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Date |
2011-09-21T12:07:27Z
2011-09-21T12:07:27Z 1992 |
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Type |
Article
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Identifier |
Protein V, a novel type-II IgG receptor from Streptococcus sp.: sequence, homologies and putative Fc-binding site / Smirnov O.Yu., Denesyuk A.I., Zakharov M.V. et al. // Gene. - 1992. - V.120. - No.1. - P. 27–32.
Protein V, a novel type-II IgG receptor from Streptococcus sp.: sequence, homologies and putative Fc-binding site (Erratum) / Smirnov O. Yu., Denesyuk A. I., Zakharov M. V. et al. // Gene. - 1993. - V.124. - No.1. - P. 149–150.
http://essuir.sumdu.edu.ua/handle/123456789/17588 |
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Language |
en
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