STAGES OF DEVELOPMENT OF STREPTOZOTOCIN-INDUCED EXPERIMENTAL DIABETES MELLITUS
Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
STAGES OF DEVELOPMENT OF STREPTOZOTOCIN-INDUCED EXPERIMENTAL DIABETES MELLITUS
|
|
| Creator |
Бойчук, Тарас Миколайович
Грицюк, Мар'яна Іванівна Гоженко, Анатолій Іванович |
|
| Subject |
diabetes mellitus
streptozotocin kidneys hyperglycemia glomerular filtration |
|
| Description |
The article presents data about the stages of experimental diabetes mellitus under conditions of the streptozotocin administration. It is noted that in the early development of experimental diabetes, changes in the kidneys proceeds in three stages: physiological adaptation; increasing morphological and functional changes and maladaptation; pathophysiological stage. The data related to changes in glomerular filtration rate, acid excretion, individual morphological alterations, etc. are given. The indicated changes in the opinion of the authors indicate an adaptive reaction of the system of regulation of water-salt metabolism and its main effector organ - the kidneys - to hyperosmia, caused by hyperglycemia with the subsequent formation of diabetic nephropathy. |
|
| Date |
2018-01-03T07:46:38Z
2018-01-03T07:46:38Z 2017 |
|
| Type |
Article
|
|
| Identifier |
ISSN 2391-8306
http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/13417 |
|
| Language |
en
|
|
| Relation |
;UDK 616.379-008.64-036-019:615.252.349.7
|
|
| Format |
application/pdf
|
|
| Publisher |
Journal of Education, Health and Sport. 2017;7(9).
|
|