Preparation of nanostructural dextran-based carrier particles for drug delivery to the lungs
Електронний науковий архів Науково-технічної бібліотеки Національного університету "Львівська політехніка"
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
Preparation of nanostructural dextran-based carrier particles for drug delivery to the lungs
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| Creator |
Jabłczyńska, Katarzyna
Widyńska, Ewelina Sosnowski, Tomasz R. |
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| Contributor |
Warsaw University of Technology
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| Subject |
nanostructural powder
particle engineering spray drying polysaccharide particles inhalation therapy |
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| Description |
Particle engineering can be used to design inhalation drug carrier that will combine advantages of nano- and microparticles. This work present a review of research on dextran-based nanostructural powder prepared using the spray drying method. The shape of powder particles is shown to depend on the applied drying process parameters and additives used. It was proved that surface morphology of particles strongly affects powder aerosolization performance. Tested powders demonstrated a good restoration of the initial nanoparticles size distribution after rehydration. All these features allow to consider dextran-based nanostructural particles as new attractive carriers for drug delivery to the lungs.
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| Date |
2018-05-02T14:31:59Z
2018-05-02T14:31:59Z 2016 |
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| Type |
Conference Abstract
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| Identifier |
Jabłczyńska K. Preparation of nanostructural dextran-based carrier particles for drug delivery to the lungs / Katarzyna Jabłczyńska, Ewelina Widyńska, Tomasz R. Sosnowski // Litteris et Artibus : proceedings of the 6th International youth science forum, November 24–26, 2016, Lviv, Ukraine / Lviv Polytechnic National University. – Lviv : Lviv Polytechnic Publishing House, 2016. – P. 398–399. – Bibliography: 3 titles.
http://ena.lp.edu.ua:8080/handle/ntb/40954 |
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| Language |
en
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| Relation |
[1] L. Gradoń, T.R Sosnowski, “Formation of particles for dry powder inhalers”, Adv. Powder Technol., vol. 25, pp. 43-55, 2014. [2] K. Jabłczyńska, M. Janczewska, A. Kulikowska, T. R. Sosnowski, ”Preparation and characterization of biocompatible polymer particles as potential nanocarriers for inhalation therapy”, Int. J. Polym. Sci., vol. 2015, article ID: 763020 (8 pages), 2015. [3] Wasiak I., Kulikowska A., Janczewska M., Michalak M., Cymerman I.A., Nagalski A., Kallinger P., Szymanski W.W., Ciach T., “Dextran nanoparticle synthesis and properties”, PLoS ONE vol. 11(1), e0146237, 2016.
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| Format |
398-399
application/pdf |
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| Coverage |
UA
Lviv |
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| Publisher |
Lviv Polytechnic Publishing House
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