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Molecular principles of the spontaneous mutagenesis in DNA

Електронний науковий архів Науково-технічної бібліотеки Національного університету "Львівська політехніка"

Переглянути архів Інформація
 
 
Поле Співвідношення
 
Title Molecular principles of the spontaneous mutagenesis in DNA
 
Creator Brovarets, Ol’ha
 
Contributor National Academy of Sciences of Ukraine
Taras Shevchenko National University of Kyiv
 
Subject spontaneous point mutagenesis
incorporation and replication errors
tautomerisation
pairs of nucleotide bases
enzymatically-competent conformation
hydrogen bond
quantum chemistry
 
Description Reported results are crucial for understanding of the microstructural mechanisms of the spontaneous transitions and transversions, since they allow us to explain, from the one side, the origin of the mutagenic tautomers at the separation of the DNA strands before its replication and, from the other side, in what way occurs the adaptation of the incorrect purine·pyrimidine, purine·purine and pyrimidine·pyrimidine wobble pairs to the enzymatically competent sizes in the recognition pocket of the high-fidelity DNA-polymerase.
 
Date 2018-04-04T12:44:44Z
2018-04-04T12:44:44Z
2016
 
Type Conference Abstract
 
Identifier Brovarets O. Molecular principles of the spontaneous mutagenesis in DNA / Ol’ha Brovarets // Litteris et Artibus : proceedings of the 6th International youth science forum, November 24–26, 2016, Lviv, Ukraine / Lviv Polytechnic National University. – Lviv : Lviv Polytechnic Publishing House, 2016. – P. 23–30. – Bibliography: 69 titles.
http://ena.lp.edu.ua:8080/handle/ntb/40240
 
Language en
 
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Format 23-30
application/pdf
 
Coverage UA
Lviv
 
Publisher Lviv Polytechnic Publishing House