Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
Vernadsky National Library of Ukraine
Переглянути архів Інформація| Поле | Співвідношення | |
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Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
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| Creator |
Burlaka, A.
Lukin, S. Prylutska, S. Remeniak, O. Prylutskyy, Yu. Shuba, M. Maksimenko, S. Ritter, U. Scharff, P. |
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| Subject |
Short communications
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| Description |
It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells. Materials and Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.78–1.40 mm and power density of 3.5 W/cm2 over 1.5 min in the presence of MWCNT (0.1 mg/ml). The changes in the temperature of suspension with the NIR exposure time was measured using the differential cooper-constantan thermocouple. The viability of EAC cells was evaluated by trypan blue staining. Results: The death of 95.2% of EAC cells in the presence of MWCNT was observed after 1.5 min of NIR light irradiation: thermal ablation temperature was ~50 °C. Conclusions: It was demonstrated that addition of MWCNT to EAC cell suspension results in the photo-ablative destruction of cells exposed to short time NIR irradiation.
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| Date |
2018-06-19T10:16:42Z
2018-06-19T10:16:42Z 2010 |
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| Type |
Article
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| Identifier |
Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ.
1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/138596 |
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en
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| Relation |
Experimental Oncology
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| Publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
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