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Photolon enhanccement of ultrasound cytotoxicity

Vernadsky National Library of Ukraine

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Поле Співвідношення
 
Title Photolon enhanccement of ultrasound cytotoxicity
 
Creator Tserkovsky, D.A.
Alexandrova, E.N.
Istomin, Yu.P.
 
Subject Short communications
 
Description Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors.
 
Date 2018-06-19T10:39:02Z
2018-06-19T10:39:02Z
2011
 
Type Article
 
Identifier Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ.
1812-9269
http://dspace.nbuv.gov.ua/handle/123456789/138614
 
Language en
 
Relation Experimental Oncology
 
Publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України