Photolon enhanccement of ultrasound cytotoxicity
Vernadsky National Library of Ukraine
Переглянути архів ІнформаціяПоле | Співвідношення | |
Title |
Photolon enhanccement of ultrasound cytotoxicity
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Creator |
Tserkovsky, D.A.
Alexandrova, E.N. Istomin, Yu.P. |
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Subject |
Short communications
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Description |
Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors.
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Date |
2018-06-19T10:39:02Z
2018-06-19T10:39:02Z 2011 |
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Type |
Article
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Identifier |
Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ.
1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/138614 |
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Language |
en
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Relation |
Experimental Oncology
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Publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
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