Neutrophil-tumor cell phagocytosis (cannibalism) in human turoms: an update and literature review
Vernadsky National Library of Ukraine
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
Neutrophil-tumor cell phagocytosis (cannibalism) in human turoms: an update and literature review
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| Creator |
Caruso, R.A.
Fedele, F. Finocchiaro, G. Arena, G. Venuti, A. |
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| Subject |
Reviews
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| Description |
The recognition and removal of apoptotic cells by tissue macrophages and nonprofessional phagocytes, in a process called efferocytosis, is critical for development, tissue homeostasis and resolution of inflammation. Apoptotic bodies arising in tumor tissue are ingested by viable neoplastic cells and by resident macrophages. We described tumor cell phagocytosis of apoptotic neutrophils in human gastric carcinomas. This phenomenon is analogous to neutrophil efferocytosis performed by macrophages and by nonprofessional phagocytes during inflammatory reaction but is distinct by other types of cell-in-cell phenomena including emperipolesis and entosis both cytologically and biologically. In this review, we discussed them in their ultrastructural morphology, physiological roles, and clinicopathologic implications. This article is part of a Special Issue entitled “Apoptosis: Four Decades Later”.
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| Date |
2018-06-19T19:04:28Z
2018-06-19T19:04:28Z 2012 |
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| Type |
Article
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| Identifier |
Neutrophil-tumor cell phagocytosis (cannibalism) in human turoms: an update and literature review / R.A. Caruso, F. Fedele, G. Finocchiaro, G. Arena, A. Venuti // Experimental Oncology. — 2012. — Т. 34, № 3. — С. 306-311. — Бібліогр.: 52 назв. — англ.
1812-9269 http://dspace.nbuv.gov.ua/handle/123456789/139087 |
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| Language |
en
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| Relation |
Experimental Oncology
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| Publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
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