Progress and chellenges in electrochemiluminescent aptasensors
Електронного архіву Харківського національного університету радіоелектроніки (Open Access Repository of KHNURE)
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
Progress and chellenges in electrochemiluminescent aptasensors
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| Creator |
Muzyka, K.
Muhammad Saqib Zhongyuan Liu Wei Zhang Guobao Xu |
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| Subject |
diagnostic and detection technologies, aptasensor, ECL
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| Description |
The importance of developing new diagnostic and detection technologies for the growing number of sensing challenges is rising each year. Here, we present a comprehensive and concise review on electrochemiluminescent (ECL) aptasensors by putting special emphasis on its characteristic features, advances, challenges, and applications of ECL based aptasensors. ECL is an ideal tool for constructing such sensors because of its inherent characteristics and can be easily integrated into aptamer based sensing platforms. This review summarizes the "synergistic benefits" of ECL aptamer-based sensors; classifications of ECL aptamer-based assay designs, and signal amplification strategies. This critical review highlights the effects of integration of nanomaterials, immobilization techniques, and amplification/detection strategies on the analytical performance of ECL based aptasensors. Moreover, several proof-of-concepts with appropriate figures and explanations have been shown to provide a general guide for the design of ECL aptasensors, and to stimulate further application of these ECL aptasensors. Finally, we conclude with the remaining challenges and opportunities to inspire further developments in ECL aptasensors. |
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| Date |
2017-11-03T07:38:14Z
2017-11-03T07:38:14Z 2017 |
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| Type |
Book
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| Identifier |
: Kateryna Muzyka, Muhammad Saqib, Zhongyuan Liu, Wei Zhang and Guobao Xu, PROGRESS AND CHALLENGES IN ELECTROCHEMILUMINESCENT APTASENSORS, Biosensors and Bioelectronic, http://dx.doi.org/10.1016/j.bios.2017.01.015
http://openarchive.nure.ua/handle/document/4069 |
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| Language |
en
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| Publisher |
PII: S0956-5663(17)30015-5 DOI: http://dx.doi.org/10.1016/j.bios.2017.01.015 Reference: BIOS9480
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