What is the role of nucleinat in a complex of control therapy of bronchial asthma in school-age children? Double-blind placebo controlled method
Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
What is the role of nucleinat in a complex of control therapy of bronchial asthma in school-age children? Double-blind placebo controlled method
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| Creator |
Bezrukov, Leonid Oleksiuovich
Koloskova, Olena Kostantunivna Marusyk, Uliana Ivanivna |
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| Subject |
children
bronchial asthma bronchial hyperresponsiveness immunity Nucleinat дети бронхиальная астма гипервосприимчивость бронхов иммунитет Нуклеинат діти бронхіальна астма гіперсприйнятливість бронхів імунітет Нуклеїнат |
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| Description |
The effect of Nucleinat on bronchial hyper-responsiveness, the parameters of the phagocytic activity and phagocytic index of neutrophils their oxygen-dependent metabolism and the blood content of nitric oxide metabolites in 98 school age children with bronchial asthma lias been studied by means of a double-blind placebo-controlled method. Two clinical groups were formed with the help of the table of accidental numbers. The first clinical group included 47 children who took Nucleinat in a dose of 0,25 g per diem during 21 days in a complex of base-line therapy. The second clinical group was formedof 51 children who took placebo according lo the same regimen. It has been shown that thanks to the use of Nucleinat a reduction of bronchial hypersensitivity and optimization of disease control have been achieved, which was indirectly evidenced by an increased risk of detecting moderate bronchial responsiveness to histamine (OR = 3.6; 95% CI: 1,3-9,3) and a decrease of the phagocytic activity of neutrophils (OR=l,9 with 95% CI (0,9-4,4)).
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| Date |
2013-04-02T19:18:29Z
2013-04-02T19:18:29Z 2010 |
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| Type |
Article
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| Identifier |
УДК 616.248-059.3-085
http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/6096 |
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| Language |
other
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| Format |
application/pdf
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| Publisher |
Буковинський медичний вісник
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