Features of exercise induced bronchial asthma course in schoolchildren with poly morphisms in glutation-S-transferase genes
Цифровий Репозиторій - Інтелектуальні Фонди Буковинського державного медичного університету
Переглянути архів Інформація| Поле | Співвідношення | |
| Title |
Features of exercise induced bronchial asthma course in schoolchildren with poly morphisms in glutation-S-transferase genes
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| Creator |
Koloskova, O.K.
Hryhola, O.G. Bilous, T.M. Ortemenka, Ye.P. |
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| Subject |
children
exercise-induced bronchial asthma glutation-S-transferase genes polymorphisms дети бронхиальная астма физического напряжения глутатион-S-трансфераза діти бронхіальна астма фізичного напруження глутатіон-S-трансфераза |
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| Description |
With respect to the principles of bioethics, on the base of allergy department of Chernivtsi Regional Children's Hospital it has been conducted a comprehensive clinical and paraclinical examination of 51 children with symptoms of exercise induced asthma phenotype depending upon the presence or the absence of genes polymorphism of the enzymes of glutation-S-transferase – GSTT1M1. The study showed that the course of the disease was more severe in the patients with deletions of the mentioned genes, though with more rapid effect of standard reliever treatments as compared to the patients with genotype GSTT1+M1+. The patients with exercise-induced asthma in the presence of deletion genes polymorphisms of GSTT1M1 (GSTT1delM1del, GSTT1+M1del or GSTT1delM1+) require a special attention to their environmental enhance¬ment and normalization of their life-style.
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| Date |
2017-06-07T13:07:30Z
2017-06-07T13:07:30Z 2014 |
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| Type |
Article
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| Identifier |
УДК 616.248-07-053.5:575.2
http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/12458 |
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| Language |
en
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| Format |
application/pdf
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| Publisher |
Буковинський медичний вісник
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